Ira J Dunkel Selected Research

Leukopenia

1/2021

A phase I trial of the CDK 4/6 inhibitor palbociclib in pediatric patients with progressive brain tumors: A Pediatric Brain Tumor Consortium study (PBTC-042).

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Ira J Dunkel Research Topics

Disease

62	Neoplasms (Cancer) 12/2023 - 02/2002
58	Retinoblastoma (Glioblastoma, Retinal) 02/2024 - 10/2003
15	Brain Neoplasms (Brain Tumor) 12/2023 - 02/2002
15	Glioma (Gliomas) 12/2023 - 05/2004
14	Medulloblastoma 01/2022 - 01/2002
8	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 09/2017 - 02/2002
7	Diffuse Intrinsic Pontine Glioma 03/2024 - 07/2017
6	Disease Progression 01/2018 - 01/2007
5	Neoplasm Metastasis (Metastasis) 02/2024 - 07/2010
5	Neuroblastoma 10/2022 - 03/2004
4	Fever (Fevers) 01/2023 - 08/2010
4	Langerhans-Cell Histiocytosis (Histiocytosis, Langerhans Cell) 01/2023 - 01/2008
4	Residual Neoplasm 01/2023 - 12/2008
4	Central Nervous System Neoplasms 01/2021 - 04/2010
4	Neutropenia 01/2021 - 08/2010
4	Melanoma (Melanoma, Malignant) 11/2020 - 04/2008
4	Astrocytoma (Pilocytic Astrocytoma) 01/2019 - 10/2006
4	Germinoma 04/2016 - 05/2004
3	Sepsis (Septicemia) 01/2021 - 03/2010
3	Exanthema (Rash) 01/2020 - 11/2017
3	Retinal Detachment (Retinal Detachments) 01/2018 - 08/2008
3	Ependymoma 07/2017 - 10/2007
3	Second Primary Neoplasms (Neoplasms, Second) 01/2016 - 10/2007
3	Primitive Neuroectodermal Tumors (PNET) 03/2008 - 01/2002
2	Rhabdomyosarcoma 10/2022 - 07/2017
2	Ewing Sarcoma (Sarcoma, Ewing) 10/2022 - 01/2017
2	Sarcoma (Soft Tissue Sarcoma) 11/2020 - 12/2018
2	Hemorrhage 01/2020 - 01/2012
2	Fatigue 11/2017 - 01/2017
2	Meningioma (Meningiomas) 08/2016 - 10/2010
2	Ototoxicity 04/2013 - 11/2011
2	Leukemia 10/2010 - 07/2007
2	Diabetes Insipidus 01/2008 - 08/2004
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 07/2007 - 03/2004
1	Slipped Capital Femoral Epiphyses 05/2023
1	Circulating Neoplastic Cells 01/2023
1	Diarrhea 01/2023
1	Vomiting 01/2023
1	Thrombocytopenia (Thrombopenia) 10/2022
1	Retinal Telangiectasis 03/2021
1	13q deletion syndrome 01/2021
1	Hypertension (High Blood Pressure) 01/2021
1	Leukopenia 01/2021

Drug/Important Bio-Agent (IBA)

18	Carboplatin (JM8)FDA LinkGeneric 11/2022 - 10/2003
12	Melphalan (Alkeran)FDA LinkGeneric 01/2024 - 08/2008
9	Topotecan (Hycamtin)FDA LinkGeneric 01/2014 - 04/2010
7	dipinacoline glutamateIBA 03/2024 - 01/2017
7	Thiotepa (Triethylenethiophosphoramide)FDA LinkGeneric 11/2022 - 05/2004
7	Etoposide (VP 16)FDA LinkGeneric 11/2022 - 03/2004
7	Retinaldehyde (Retinal)IBA 01/2018 - 08/2008
5	Cyclophosphamide (Cytoxan)FDA LinkGeneric 10/2022 - 08/2004
4	Circulating Tumor DNAIBA 02/2024 - 03/2021
4	Cell-Free Nucleic AcidsIBA 01/2023 - 01/2020
4	dabrafenibIBA 01/2023 - 01/2018
3	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 01/2020
3	AZD 6244IBA 08/2022 - 01/2019
3	perifosineIBA 07/2017 - 01/2017
3	Tumor Biomarkers (Tumor Markers)IBA 05/2014 - 08/2006
3	Alkylating AgentsIBA 04/2010 - 02/2002
3	Vincristine (Oncovin)FDA LinkGeneric 06/2008 - 01/2007
3	Cisplatin (Platino)FDA LinkGeneric 06/2008 - 08/2004
2	IpilimumabIBA 01/2023 - 11/2017
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 10/2021 - 12/2019
2	Phosphotransferases (Kinase)IBA 01/2020 - 12/2019
2	Proteins (Proteins, Gene)FDA Link 01/2016 - 03/2011
2	Monoclonal AntibodiesIBA 12/2008 - 02/2002
2	Immunoglobulins (Immunoglobulin)IBA 12/2008 - 02/2002
2	Carmustine (FIVB)FDA Link 12/2008 - 05/2004
1	PanobinostatIBA 12/2023
1	Tyrosine Kinase InhibitorsIBA 05/2023
1	Biomarkers (Surrogate Marker)IBA 01/2023
1	B7-H1 AntigenIBA 01/2023
1	NivolumabIBA 01/2023
1	CreatinineIBA 01/2023
1	trametinibIBA 01/2023
1	serum P-component (CIt)IBA 10/2022
1	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2022
1	Isotretinoin (Accutane)FDA LinkGeneric 01/2022
1	Vorinostat FDA Link 01/2022
1	Filgrastim (Neupogen)FDA Link 01/2021
1	Alanine Transaminase (SGPT)IBA 01/2021
1	Cyclin-Dependent Kinase 4IBA 01/2021
1	palbociclibIBA 01/2021
1	Everolimus FDA Link 01/2021
1	ribociclibIBA 01/2021
1	pomalidomideIBA 01/2021

Therapy/Procedure

59	Drug Therapy (Chemotherapy) 02/2024 - 01/2002
30	Therapeutics 01/2023 - 03/2004
26	Radiotherapy 01/2023 - 02/2002
8	Aftercare (After-Treatment) 02/2024 - 08/2008
4	Craniospinal Irradiation 09/2017 - 06/2008
3	Induction Chemotherapy 01/2023 - 03/2008
3	Radioimmunotherapy 01/2018 - 12/2007
3	Brachytherapy 11/2013 - 08/2008
2	Re-Irradiation 03/2024 - 11/2011
2	Eye Enucleation (Enucleation, Eye) 01/2023 - 01/2020
2	Platelet Transfusion (Blood Platelet Transfusions) 10/2022 - 01/2021
2	Adjuvant Chemotherapy 01/2019 - 07/2007
2	Salvage Therapy 01/2016 - 11/2012
1	Treatment Delay 03/2021